Phase II Study of VELCADE for Relapsed or Refractory T-cell Prolymphocytic Leukemia
NCT01162031 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2018-05-21
Summary
We hope to learn more about the clinical efficacy of bortezomib in T-cell prolymphocytic leukemia. Patients will be selected as a possible participant in this study because they have a bone marrow disorder known as T-cell prolymphocytic leukemia (T-cell PLL) which does not tend to respond well to conventional treatment with chemotherapy.
Conditions
- Leukemia
- Acute Lymphocytic Leukemia
Interventions
- DRUG
-
IV
Sponsors & Collaborators
-
Millennium Pharmaceuticals, Inc.
collaborator INDUSTRY - lead OTHER
Principal Investigators
-
Bruno Carneiro de Medeiros · Stanford University
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-06-30
- Primary Completion
- 2011-07-31
- Completion
- 2011-07-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantation
NCT02312102 ·Status: COMPLETED ·Phase: PHASE1
-
Preemptive Strike With Bortezomib in Multiple Myeloma Patients
NCT00657553 ·Status: TERMINATED ·Phase: PHASE3
-
VELCADE in MALT Lymphoma Pretreated With More Than One Prior Systemic Therapy
NCT00210392 ·Status: TERMINATED ·Phase: PHASE2
-
VELCADE in MALT Lymphoma Pretreated With Prior Systemic Therapy
NCT00210327 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase II Study of VELCADE (Bortezomib) in Combination With Bendamustine and Rituximab in Subjects With Relapsed or Refractory Follicular Lymphoma
NCT00636792 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of VELCADE Given as Retreatment to Multiple Myeloma Patients for Efficacy, Safety and Tolerability
NCT00257114 ·Status: COMPLETED ·Phase: PHASE4
-
Bortezomib (Velcade) in Patients With Untreated Multiple Myeloma
NCT00153920 ·Status: COMPLETED ·Phase: PHASE2
-
Velcade (Bortezomib - PS341) in the Treatment of Patients Over 18 Years With Ph+ Leukemia
NCT00511069 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib for the Treatment of Refractory Chronic Graft-vs-Host Disease(cGVHD)
NCT01158105 ·Status: UNKNOWN ·Phase: PHASE2
-
Safety and Efficacy Study of Single Weekly Bortezomib in Newly Diagnosed Multiple Myeloma
NCT01090921 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib (Velcade) in Waldenstrom's Macroglobulinemia
NCT00142129 ·Status: COMPLETED ·Phase: PHASE2
-
An Open-Label Study to Assess the Effect of CYP3A4 Induction on the Pharmacokinetics of VELCADE (Bortezomib)
NCT00608907 ·Status: COMPLETED ·Phase: PHASE1
-
Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrome
NCT01075425 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Velcade and Thalidomide in Patients With Myelodysplasia
NCT00271804 ·Status: TERMINATED ·Phase: PHASE1
-
VELCADE/Melphalan/Prednisone Versus Melphalan/Prednisone in Patients With Previously Untreated Multiple Myeloma
NCT00111319 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Bortezomib Combined With ACVBP in Peripheral T-cell Lymphoma
NCT00136565 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib and Vorinostat in Treating Patients With High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia
NCT00818649 ·Status: TERMINATED ·Phase: PHASE2
-
Velcade in MALT Lymphoma Patients
NCT00373906 ·Status: COMPLETED ·Phase: PHASE2
-
Azacytidine and Bortezomib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes
NCT00624936 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Study of Velcade, Decadron, and Doxil Followed by Cyclophosphamide in Multiple Myeloma
NCT00148317 ·Status: COMPLETED ·Phase: PHASE2
-
Velcade (Bortezomib) Consolidation After Transplant
NCT01539083 ·Status: COMPLETED ·Phase: PHASE3
-
Repeat-Dose Pharmacokinetics and Pharmacodynamics of Bortezomib in Patients With Relapsed Multiple Myeloma
NCT00080405 ·Status: COMPLETED ·Phase: PHASE1
-
Weekly Bortezomib (Velcade) in the Treatment of Patients With Refractory Multiple Myeloma
NCT00193557 ·Status: COMPLETED ·Phase: PHASE2
-
Bortezomib in Treating Patients With Myelodysplastic Syndromes
NCT00262873 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate Two Different Regimens of VELCADE in Combination With Dexamethasone, Thalidomide and Cyclophosphamide (VDT vs VDTC) in Newly Diagnosed Multiple Myeloma
NCT00531453 ·Status: COMPLETED ·Phase: PHASE2