Autoimmune Diabetes: Markers of the Disease and Treatment of Latent Autoimmune Diabetes in Adults (LADA)
NCT01148238 · Status: WITHDRAWN · Type: OBSERVATIONAL
Last updated 2012-12-10
Summary
Autoimmunity is the main cause of diabetes type 1 and an important factor as cause of Latent Autoimmune Diabetes in Adults (LADA). Recently, research has found that being deficient of T-reg cells is an important cause of autoimmunity. The study hypothesis are:
1. Patients with newly found diabetes type 1 have less T-reg than healthy.
2. Patients with newly found diabetes type 1 have less T-reg than patients with long duration of the illness.
3. The number of T-reg is negative associated with HLA-risk-haplotype.
4. The number of T-reg is negative associated with LADA.
5. Differences relating to inflammatory cytokines will be seen among patients with newly found diabetes type 1, but not among others.
Conditions
- Autoimmune Diabetes
Sponsors & Collaborators
-
Norwegian University of Science and Technology
lead OTHER
Principal Investigators
-
Valdemar Grill, M.D, PhD · Department of Cancer Research and Molecular Medicine
Eligibility
- Min Age
- 30 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-08-31
- Primary Completion
- 2012-12-31
- Completion
- 2012-12-31
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