The Effects of Spirulina Platensis on Insulin Resistance in HIV-infected Patients

Summary

Spirulina, a widely used food supplement, improves the lipid profile and glycemic control in people living with diabetes, suggesting that it could have some effects on insulin sensitivity. Since HIV-infected patients develop metabolic abnormalities due to the virus and/or to antiretroviral (ARV) drugs, the investigators therefore proposed to evaluate the effect that spirulina can have on HIV/HAART-associated insulin resistance

Conditions

• Insulin Resistance
• HIV/AIDS

Interventions

DIETARY_SUPPLEMENT

Spirulina platensis

Subjects received 19g daily of supplement averagely.This was supplied as powder daily, in packs that lasted for 2weeks each. Each subject was therefore seen every two week to obtain new stock of supplements and evaluate compliance

DIETARY_SUPPLEMENT

Soya bean

Each subject received 19g of supplement on average daily. Subjects were seen every two weeks to evaluate compliance and obtain a new stock.

Sponsors & Collaborators

• University of Yaounde

  collaborator OTHER

• Antenna Technologies

  collaborator UNKNOWN

• Yaounde Central Hospital

  lead OTHER_GOV

Principal Investigators

• Pr Jean Claude Mbanya, MD, PhD · International diabetes federation/ Director, National Obesity Centre, Yaounde Central Hospital, Cameroon

• Dr Sobngwi Eugene, MD, PhD · Consultant Endocrinologist, National Obesity Centre/ Senior Lecturer, University of Yaounde 1, Cameroon and Newcastle University, UK

• Dr Marcel Azabji Kenfack, MD · Dep. of Physiologie, Faculty of Medicine and Biomedical Sciences University Yaoundé I, Cameroon

• Dr Gabriel Loni Ekali, MD · National Obesity Centre, Yaounde Central Hospital, Cameroon

Study Design

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

21 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2008-10-31

Primary Completion

2009-02-28

Completion

2009-02-28

Countries

• Cameroon

Study Locations