MedTrace Logo

The Effect of Weight Loss on Psoriasis Area Severity Index in Adult Psoriasis Patients

NCT01137448 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2013-12-16

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effect that weight loss has on the severity of psoriasis in obese subjects. Fifty obese (BMI equal to or greater than 30) patients with moderate to severe plaque psoriasis will be enrolled in a weight loss intervention program. The severity of their psoriasis will be reevaluated at month 3 and month 6 of the program to determine what effect weight loss has had on their psoriasis. Serum TNF-alpha will be measured at month 0 and month 6. The hypothesis that will be tested is that weight loss will lead to a significant improvement in the severity of psoriasis and a reduction in TNF-alpha levels.

Conditions

Interventions

BEHAVIORAL

Weight Loss

Subjects will enroll in a weight loss program and participate in weight loss counseling 6 times over the course of 6 months.

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • The University of Texas Health Science Center, Houston

    lead OTHER

Principal Investigators

  • Adelaide Hebert, MD · University of Texas Medical School - Houston

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-06-30
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01137448 on ClinicalTrials.gov