Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar
NCT01125137 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2024-04-30
Summary
Purpose:
To compare the levels of matrix metalloproteinase-1 (MMP-1), MMP-8, MMP-13 and tissue inhibitor of metalloproteinases (TIMPs) in keloid skin tissue with normal skin in the same patient and with normal discarded skin tissue (control). The investigators aim to correlate between levels of MMPs in patients with keloid scarring in comparison with normal and discarded tissue.
Conditions
- Keloid
Interventions
- PROCEDURE
-
Removal of Keloid
Keloid will be excised by Henry Ford Hospital Dermatologist, Dermatosurgeon or Plastic Surgeon.
Sponsors & Collaborators
-
Henry Ford Health System
lead OTHER
Principal Investigators
-
Iltefat Hamzavi, M.D. · Henry Ford Hospital
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-02-28
- Primary Completion
- 2011-01-31
- Completion
- 2011-01-31
Countries
- United States
Study Locations
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