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Genetics of the Early and Late Response to Allergen Challenge

NCT01113697 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 520

Last updated 2023-12-06

No results posted yet for this study

Summary

The investigators are investigating the early and late responses to allergen challenge. The research participants who the investigators will study (from three cohorts) will be part of independently-approved studies involving allergen challenge. Due to the uniqueness of the cohorts for novel genetic study, it is logical that the investigators should initially undertake hypothesis-generating experiments. The investigators will obtain blood samples from the participants, both pre-challenge and post-challenge. The investigators will determine gene expression and protein differences between these samples, and investigate if there are inherited genetic differences between individuals that may predict their specific responses to allergens.

Conditions

Sponsors & Collaborators

  • Allergy, Genes and Environment Network (AllerGen)

    collaborator UNKNOWN

  • Networks of Centres of Excellence of Canada

    collaborator OTHER

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Scott J. Tebbutt, Ph.D · University of British Columbia

  • Gail M. Bauvreau, Ph.D · McMaster University

  • Anne K. Ellis, MD · Queen's University

  • Christopher R. Carlsten, MD · University of British Columbia

  • Danuta Radzioch, Ph.D · McGill University

Eligibility

Min Age
19 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01113697 on ClinicalTrials.gov