Vitamin D in Pregnancy and Lactation

Summary

Background: Vitamin D is vital throughout pregnancy and lactation for both maternal and infant health. Health Canada recommends women take the AI of 5ug/day of vitamin D during pregnancy, however, it is unknown how much vitamin D is necessary to ensure both mother and baby reach a vitamin D serum concentration of 25OHD\>75nmol/L.

Conditions

• Vitamin D Deficiency

Interventions

DRUG

Vitamin D

10 ug/day Vitamin D as part of standard pre-natal vitamin supplement, taken from 18 weeks gestation to 6 months postpartum.

DRUG

Vitamin D3

25 ug/day Vitamin D as part of standard pre-natal vitamin supplement, taken from 18 weeks gestation to 6 months postpartum.

DRUG

Vitamin D

50 ug/day Vitamin D as part of standard pre-natal vitamin supplement, taken from 18 weeks gestation to 6 months postpartum.

Sponsors & Collaborators

• Canadian Institutes of Health Research (CIHR)

  collaborator OTHER_GOV

• University of British Columbia

  lead OTHER

Principal Investigators

• Tim Green, Dr. · University of British Columbia

• Sheila M. Innis, Dr. · University of British Columbia

• Michael R. Lyon, MD · University of British Columbia

• Antonia W. Shand, Dr · University of British Columbia

• Peter von Dadelszen, MD · University of British Columbia

• Russ Freisen, MSc · University of British Columbia

• Kaitlin March · University of British Columbia

• Tina Li · University of British Columbia

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

42 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2010-03-31

Primary Completion

2012-08-31

Completion

2013-02-28

Countries

• Canada

Study Locations