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Influence of Selenium on Prostate Cancer Related Biomarkers

NCT01112449 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 130

Last updated 2015-07-10

No results posted yet for this study

Summary

Penn State Milton S. Hershey Medical Center researchers are trying to compare the effects of two different forms of selenium (selenium yeast and selenomethionine) on blood selenium levels and biomarkers of oxidative stress as primary endpoints. One in six men are at risk of getting prostate cancer in their lifetime. Participants will be asked to take over-the-counter selenium yeast supplements and selenomethionine or a placebo for nine out of twelve months.

Conditions

  • Effect of Selenium on Oxidative Stress in Healthy Men

Interventions

OTHER

Placebo

no active medication

DIETARY_SUPPLEMENT

selenomethionine

200 µg/day of selenomethionine (SM)

DIETARY_SUPPLEMENT

low dose selenized-yeast

200 µg/day of SY

DIETARY_SUPPLEMENT

high dose selenized-yeast

285 µg/day of SY

Sponsors & Collaborators

  • Milton S. Hershey Medical Center

    lead OTHER

Principal Investigators

  • Karam El-Bayoumy, PhD · Penn State College of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
20 Years
Max Age
79 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-05-31
Primary Completion
2012-07-31
Completion
2014-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01112449 on ClinicalTrials.gov