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The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy

NCT01106547 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2011-10-13

No results posted yet for this study

Summary

The purpose of this study is to evaluate the effect of 125 mg methylprednisolone, given intravenously 60-90 minutes before abdominal surgery,on the postoperative rehabilitation after abdominal hysterectomy.Sodium Chloride is the placebo. The following parameters are registered:

1. Pain 3, 6 and 24 hours postoperatively and 2-7 days after surgery.
2. The postoperative use of additional analgesics.
3. Inflammatory parameters before and after surgery.
4. Time until mobilization.
5. Time until discharge.

Conditions

  • Hysterectomy
  • Methylprednisolone
  • Postoperative Pain

Interventions

DRUG

Methylprednisolone 125mg

Single dose 60-90 minutes preoperatively

DRUG

Sodium Chloride 2 ml

Single dose 60-90 min preoperatively

Sponsors & Collaborators

  • Holbaek Sygehus

    lead OTHER

Principal Investigators

  • Niels Jørgen Secher, Professor · Department of Obstetrics, Hvidovre Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2011-09-30
Completion
2011-10-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01106547 on ClinicalTrials.gov