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B-vitamins Treatment for Improvement of Cognitive Function

NCT01095211 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 79

Last updated 2018-05-11

No results posted yet for this study

Summary

Observation studies documented a correlation between plasma concentrations of homocysteine and cognitive decline with age. The study hypothesis was that high doses of B-vitamins (as effective homocysteine lowering treatment) can improve cognitive function in elderly people.

Conditions

  • Cognitive Function
  • Metabolic Improvements

Interventions

DRUG

B-vitamin complex

5 mg Folic acid, plus 1 mg cyanocobalamin and 40 mg vitamin B6) oral/ day. The placebo capsule contained 400 mg of mannitol: aerosil (99.5: 0.5). In addition, 1 mg/s.c cyanocobalamin daily

Sponsors & Collaborators

  • Geriatrische Rehaklinik

    collaborator UNKNOWN

  • Universität des Saarlandes

    lead OTHER

Principal Investigators

  • Rima Obeid · Department of Clinical Chemistry, University of Saarland

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-01-31
Primary Completion
2005-09-30
Completion
2009-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01095211 on ClinicalTrials.gov