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FLOTRAC/VIGILEO in Acute Circulatory Failure

NCT01090791 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1

Last updated 2016-09-08

No results posted yet for this study

Summary

Acute circulatory failure may be related to hypovolemia. Fluid loading increases stroke volume in approximatively half of challenges. Determining fluid responsiveness prevents unnecessary fluid loading. Passive leg raising (PLR) provides a transient increase of 300 ml in venous return for a short time. The measurement of stroke volume (SV) before and after a PLR test allows physician to detect fluid responsiveness, when stroke volume increases is higher than 15 %. Beside thermodilution, the use of non invasive device to measure stroke volume becomes largely employed. Arterial Pressure based Cardiac Output (APCO), provided by the Flotrac/Vigileo system, does not required specific materials nor repeated calibration. The third generation software is believed to be more accurate and more precise for SV measurement. The aim of this study is to test the performance of the Flotrac/Vigileo device in a situation of rapid venous return changes induced by PLR and then by fluid loading. Patients will be classify posteriorly in responders and non responders, according to the magnitude of the fluid loading-induced SV changes measured by transthoracic echocardiography.

Conditions

  • Critically Ill
  • Acute Circulatory Failure
  • Fluid Loading

Interventions

DEVICE

Flotrac/Vigileo third generation software

Measurement of stroke volume according to the arterial pressure waveform

DEVICE

Transthoracic echocardiography

Measurement of stroke volume according to the aortic time-velocity integral

Sponsors & Collaborators

  • Hôpital Européen Marseille

    lead OTHER

Principal Investigators

  • Jérôme Allardet-Servent, MD,MSc · Fondation Hôpital Ambroise Paré

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-05-31
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01090791 on ClinicalTrials.gov