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Regulation of Intraarticular and Synovium-related Biomarkers of Osteoarthritis. Effect of Acute Mechanical Joint Loading

NCT01090375 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL

Last updated 2010-03-19

No results posted yet for this study

Summary

In the present study the microdialysis method is used to investigate biochemical changes within and around the joint simultaneously in both the resting state and in a joint that had been subjected to exercise. The aim of the present study was, by applying the microdialysis technique, to monitor markers of cartilage breakdown and inflammation in 2 different positions of the knee (inside and in the inner part of the knee capsule) in a group of human females with knee osteoarthritis over a period of 3 hours.

Conditions

Interventions

OTHER

Exercise

OTHER

Non Exercise

Sponsors & Collaborators

  • The Danish Rheumatism Association

    collaborator OTHER

  • Danish Ministry of Health, Internal Affairs

    collaborator UNKNOWN

  • Danish National Research Council

    collaborator UNKNOWN

  • The Danish Medical Research Council

    collaborator OTHER

  • Bispebjerg Hospital

    lead OTHER

Study Design

Purpose
BASIC_SCIENCE
Model
PARALLEL

Eligibility

Min Age
55 Years
Max Age
75 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-08-31
Primary Completion
2009-03-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01090375 on ClinicalTrials.gov