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Risk Factors for Foot Ulceration in the Chronic Kidney Disease (CKD) Population

NCT01089829 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2010-03-19

No results posted yet for this study

Summary

Foot ulceration is a risk factor that has been associated with early death in patients with chronic kidney disease. Little is known about the relationship between these risk factors that develop in patients with kidney failure and the onset of lower limb threatening foot ulcers.

Diabetes is a major cause of both kidney disease and foot ulceration; however a previous study reported that a significant proportion of kidney failure patients on haemodialysis treatment without a diagnosis of diabetes also had these risk factors that could lead to foot ulceration.

The aim of this study will be to identify these risk factors associated with lower limb threatening disease in patients with advanced kidney failure. In addition a robust screening tool will be developed to address the reliability and validity of current screening methods deemed to be gold standard in the assessment of diabetic foot disease in this Chronic Kidney Disease population.

It is important to follow the progression of these risk factors as the kidney failure worsens. The study also intends to screen patients as they start dialysis treatment and follow their progress with respect to risk factors known to predispose to foot ulceration over their first year of treatment. The proposed outcome from this study is to develop a strategy to identify patients with kidney failure that are at risk of foot ulceration and intervene at an early point to prevent the life threatening complications associated foot disease.

Conditions

Interventions

OTHER

Foot examination

Non-invasive neurological sensory testing Non-invasive doppler assessment of peripheral arterial system

Sponsors & Collaborators

  • Podiatry Department, Cardiff & Vale University Health Board

    collaborator UNKNOWN

  • School of Health Sciences, UWIC

    collaborator UNKNOWN

  • Institute of Nephrology, Cardiff & Vale University Health Board

    collaborator UNKNOWN

  • Cardiff University

    lead OTHER

Principal Investigators

  • Ian DR Mathieson · School of Health Sciences, UWIC

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-04-30
Primary Completion
2014-12-31
Completion
2015-12-31

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01089829 on ClinicalTrials.gov