Paracrine Mechanisms of Bone Marrow Stem Cell Signalling in Chronic Heart Failure
NCT01086787 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 125
Last updated 2010-06-11
Summary
The investigators hypothesize that chronic heart failure is associated with a general stem cell dysfunction, which translates into reduced paracrine function of adult stem cells from patients with chronic heart failure as compared to patients with preserved systolic function.
Conditions
Interventions
- OTHER
-
Surgery
Patients undergoing surgery for either cardiac surgery or orthopedic surgery
Sponsors & Collaborators
-
University Medical Center Groningen
lead OTHER
Principal Investigators
-
W. T. Ruifrok, MD · University Medical Center Groningen
-
R. A. de Boer, MD, PhD · University Medical Center Groningen
-
W. H. van Gilst, PhD · University Medical Center Groningen
-
M. Gnecchi, MD, PhD · University of Pavia
-
L. Kleijn, MD · University Medical Center Groningen
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-08-31
- Primary Completion
- 2011-08-31
- Completion
- 2011-12-31
Countries
- Italy
- Netherlands
Study Locations
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