Paracrine Mechanisms of Bone Marrow Stem Cell Signalling in Chronic Heart Failure

NCT01086787 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 125

Last updated 2010-06-11

No results posted yet for this study

Summary

The investigators hypothesize that chronic heart failure is associated with a general stem cell dysfunction, which translates into reduced paracrine function of adult stem cells from patients with chronic heart failure as compared to patients with preserved systolic function.

Conditions

Interventions

OTHER

Surgery

Patients undergoing surgery for either cardiac surgery or orthopedic surgery

Sponsors & Collaborators

  • University Medical Center Groningen

    lead OTHER

Principal Investigators

  • W. T. Ruifrok, MD · University Medical Center Groningen

  • R. A. de Boer, MD, PhD · University Medical Center Groningen

  • W. H. van Gilst, PhD · University Medical Center Groningen

  • M. Gnecchi, MD, PhD · University of Pavia

  • L. Kleijn, MD · University Medical Center Groningen

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-08-31
Primary Completion
2011-08-31
Completion
2011-12-31

Countries

  • Italy
  • Netherlands

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01086787 on ClinicalTrials.gov