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Resistance Training in Intradialysis Patients

NCT01065389 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 46

Last updated 2013-09-10

No results posted yet for this study

Summary

Dialysis patients usually have peripheral muscle weakness due to metabolic disturbances (increased protein catabolism) and fatigue. This muscle weakness may decrease functional capacity and quality of life. It also serves to increase cardiovascular risk factors in these end stage renal disease patients. Peripheral muscle strength training shall combat physical inactivity during dialysis. In the investigators trial, the investigators hypothesis that peripheral muscle training might regulate protein catabolic rate,renal functions, cardiovascular risk factors, improve functional capacity and quality of life in endstage renal disease patients undergoing dialysis.

Conditions

Interventions

BEHAVIORAL

Progressive Resistance Exercise Training

Progressive Resistance Exercise Training thrice a week for 12 weeks. For first two weeks, 60% of 5 repetition maximum, progressing at 5% of 5 repetition maximum each week reaching upto 110% of 5 Repetition maximum at the end of 12 weeks

BEHAVIORAL

Unstructured Nonprogressive resistance exercise

Unstructured Resistance Exercise 30 minutes a day, thrice a week for 12 weeks. For 12 weeks, 20% 5 repetition maximum (which will not induce training effect and any physiological responses)and free range of motion exercises with no progression.

Sponsors & Collaborators

  • Sikkim Manipal University

    lead OTHER

Principal Investigators

  • Baskaran Chandrasekaran, MPT · Lecturer / Consultant cardiopulmonary Physiotherapist

  • Bidhan C Sharma, MPT · Assistant Professor/ Consultant Physiotherapist

  • Manish Goon, BPT · Clinical Physiotherapist

  • Nikita Joshi, MPT · Head of Department/ Associate Professor

  • Arpan Battacharia, MD · Dialysis Unit Incharge

  • Bidita Kandelwal, MD · Head of Medicine Department

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-10-31
Primary Completion
2015-04-30
Completion
2016-08-31

Countries

  • India

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01065389 on ClinicalTrials.gov