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Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells

NCT01064219 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2013-11-05

No results posted yet for this study

Summary

Intrauterine injection of hCG around the time of implantation may increase endometrial Treg cells and improve implantation. It has been demonstrated that regulatory T cells expand during pregnancy. hCG was found to be secreted by the embryo immediately after fertilization and has chemoattractant properties to Treg cells.

Conditions

Interventions

DRUG

human chorionic gonadotrophin

intrauterine injection of 100 IU hCG followed by endometrial biopsy .

Sponsors & Collaborators

  • The Egyptian IVF-ET Center

    lead OTHER

Principal Investigators

  • Ragaa Mansour, MD,PhD · The Egyptian IVF-ET Center

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
38 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-02-28
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01064219 on ClinicalTrials.gov