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Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

NCT01060969 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 55

Last updated 2012-09-10

No results posted yet for this study

Summary

To evaluate the additive value of tadalafil given together with Diamox (acetazolamide) in preventing acute mountain sickness in travelers to high altitude areas.

Conditions

  • Pulmonary Edema
  • Cerebral Edema

Interventions

DRUG

Tadalafil and acetazolamide

Experimental arm: Tadalafil 20 mg daily + acetazolamide 125 mg BID beginning above 3000 m altitude.

DRUG

Acetazolamide

Active comparator arm (control): acetazolamide 125 mg BID beginning above 3000 m altitude

Sponsors & Collaborators

  • Sheba Medical Center

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2010-08-31
Completion
2010-08-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01060969 on ClinicalTrials.gov