Effect of 4 Weeks Treatment With Acipimox in Patients With Chronic Heart Failure
NCT00549614 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2009-10-07
Summary
The primary objective of this study is to evaluate whether metabolic modulation improves left ventricular function, work capacity, insulin sensitivity and modifies substrate metabolism in chronic heart failure
Conditions
Interventions
- DRUG
-
acipimox
capsule, 250 mg, 4 times daily for 28 days
- DRUG
-
capsule, 250 mg, 4 times daily for 28 days
Sponsors & Collaborators
-
University of Aarhus
lead OTHER
Principal Investigators
-
Mads Halbirk · B-research, Aarhus Universityhospital, skejby
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 30 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-10-31
- Primary Completion
- 2008-12-31
- Completion
- 2009-05-31
Countries
- Denmark
Study Locations
More Related Trials
-
A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
NCT07218627 ·Status: RECRUITING ·Phase: PHASE1
-
Safety and Efficacy of APL180 in Healthy Volunteers and Patients With Coronary Heart Disease (CHD)
NCT00568594 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Withdrawal of Pharmacological Treatment in Patients Responding to Cardiac Resynchronization Therapy:
NCT05151861 ·Status: UNKNOWN ·Phase: PHASE4
-
Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
NCT04915365 ·Status: UNKNOWN ·Phase: PHASE3
-
Effects of Acute and Chronic Empagliflozin Heart Failure
NCT05553938 ·Status: RECRUITING ·Phase: PHASE1
-
Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM
NCT06081894 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Predicting Successful Sleep Apnea Treatment With Acetazolamide in Heart Failure Patients
NCT01377987 ·Status: COMPLETED ·Phase: NA
-
Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure
NCT03036124 ·Status: COMPLETED ·Phase: PHASE3
-
Safety and Efficacy Study of Once and Twice Daily Doses of MCC-135 in Subjects With Congestive Heart Failure.
NCT00050076 ·Status: COMPLETED ·Phase: PHASE2
-
PROCLAIM: Effect of AC2592 Administered by Continuous Subcutaneous Infusion in Subjects With Advanced Chronic Congestive Heart Failure
NCT00099580 ·Status: COMPLETED ·Phase: PHASE2
-
Reversal of Complete Heart Block With Aminophylline in Inferior Wall Myocardial Infarction Patients
NCT05666219 ·Status: WITHDRAWN ·Phase: PHASE4
-
A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure
NCT05659264 ·Status: COMPLETED ·Phase: PHASE1
-
Empagliflozin Versus Placebo on the Rate of Arrhythmic Events in Heart Failure Patients
NCT03271879 ·Status: UNKNOWN ·Phase: PHASE4
-
Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure
NCT00259038 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults
NCT04996719 ·Status: COMPLETED ·Phase: PHASE1
-
Empagliflozin in Hypertrophic Cardiomyopathy
NCT05182658 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack.
NCT04564742 ·Status: COMPLETED ·Phase: PHASE3
-
IC14 for Treatment of Acute Decompensated Heart Failure
NCT06556810 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Phase IIb Study of AZD5462 in Patients With Chronic Heart Failure
NCT06299826 ·Status: COMPLETED ·Phase: PHASE2
-
Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure
NCT00077948 ·Status: TERMINATED ·Phase: PHASE3
-
Safety of Single Intravenous Administration of S95010 in Human Healthy Volunteers
NCT03494712 ·Status: COMPLETED ·Phase: PHASE1
-
ALP-1 Continuous Intravenous Infusion to Maintain Clinical Stability in Advanced Heart Failure
NCT00610051 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
A Study of CLR325 in Chronic Stable Heart Failure Patients.
NCT02696967 ·Status: COMPLETED ·Phase: PHASE2
-
Effectiveness of Oral Anticoagulants in Elderly Patients With Non-Valvular Atrial Fibrillation and Heart Failure
NCT03508271 ·Status: COMPLETED
-
Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
NCT06535529 ·Status: RECRUITING ·Phase: PHASE3