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Acute and Chronic Effect of His-pacing in Consecutive Patients With AV-block

NCT01019213 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2012-05-15

No results posted yet for this study

Summary

Conventional right ventricular (RV) apical pacing may result in asynchronous ventricular contraction with delayed left ventricular activation, interventricular motion abnormalities, and worsening of left ventricular ejection fraction. His pacing is preserving a synchronous contraction and may prevent a decrease in left ventricular ejection fraction.

Hypothesis: His-pacing preserves left ventricular function and is a feasable alternative compared to RV septal septal pacing in patients with AV-block.

Conditions

  • Atrioventricular Block

Interventions

OTHER

Septal pacing

Septal lead activated

OTHER

His lead activated

His lead will be activated 80 ms before septal lead

Sponsors & Collaborators

  • Danish Heart Foundation

    collaborator OTHER

  • Aarhus University Hospital Skejby

    lead OTHER

Principal Investigators

  • Torsten T Nielsen, Professor · Dept. B Skejby Hospital

  • Jens C Nielsen, Phycisian · Aarhus university Hospital Skajby

  • Mads B Kronborg, Phycisian · Aarhus University Hospital Skejby

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-09-30
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01019213 on ClinicalTrials.gov