The Effect of Uric Acid Decrement on Endothelial Function in Patients With Chronic Renal Failure
NCT00978653 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2009-09-22
Summary
In this prospective study, the investigators aimed to evaluate the effects of improved hyperuricemia, a minor cardiovascular risk factor, on endothelial dysfunction in patients with chronic kidney disease.
Conditions
- Hyperuricemia
- Chronic Kidney Disease
Interventions
- DRUG
-
allopurinol
150 mg once a day
Sponsors & Collaborators
-
Istanbul University
lead OTHER
Principal Investigators
-
Berna Yelken, MD · Division of Nephrology, Istanbul Faculty of Medicine, Istanbul University
-
Yasar Caliskan · Division of Nephrology, Istanbul Faculty of Medicine, Istanbul University
-
Alaattin Yildiz, Prof, MD · Division of Nephrology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University
-
Numan Gorgulu, MD · Division of Nephrology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University
Study Design
- Allocation
- NA
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-04-30
- Primary Completion
- 2009-03-31
- Completion
- 2009-05-31
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Allopurinol in Chronic Heart Failure
NCT00997542 ·Status: COMPLETED ·Phase: PHASE4
-
Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels
NCT00987415 ·Status: COMPLETED ·Phase: PHASE2
-
Hyperuricemia and Diabetic Nephropathy
NCT04799925 ·Status: UNKNOWN
-
The Impact of Urate-lowering Therapy on Kidney Function (IMPULsKF)
NCT03336203 ·Status: UNKNOWN ·Phase: PHASE4
-
Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms
NCT04012294 ·Status: UNKNOWN ·Phase: PHASE3
-
Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease
NCT03865407 ·Status: TERMINATED ·Phase: PHASE2
-
Anakinra vs Prednisone to Treat Gout Flare in Patients With Chronic Kidney Disease Stage 4/5 or Renal Transplantation
NCT04844814 ·Status: SUSPENDED ·Phase: PHASE2
-
Prednisone for Heart Failure Patients With Hyperuricemia
NCT00919243 ·Status: COMPLETED ·Phase: PHASE4
-
Prednisone for Heart Failure Patients With Hyperuricemia
NCT02129764 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Investigation of the Atherogenic Effects of Uric Acid-modified in Endothelial Dysfunction and the the Preventional Mechanism by Anthocyanidines
NCT02797028 ·Status: UNKNOWN ·Phase: PHASE4
-
Treatment of Hyperuricemia in Patients With Heart Failure
NCT00422318 ·Status: COMPLETED ·Phase: PHASE4
-
A Prospective Cohort Study of China Serum Uric Acid Levels
NCT03616769 ·Status: COMPLETED
-
Uric Acid Study in Healthy Male Volunteers
NCT00738842 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine Excretion
NCT02752633 ·Status: COMPLETED ·Phase: PHASE4
-
Allopurinol and Pathogenesis of Cirrhosis
NCT07033533 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency
NCT01407874 ·Status: COMPLETED ·Phase: PHASE2
-
The Relationship Between Uric Acid and Inflammatory Markers
NCT01323335 ·Status: COMPLETED ·Phase: PHASE1
-
Allopurinol and Endothelial Function in Diabetic CAD Patients
NCT03385135 ·Status: UNKNOWN ·Phase: NA
-
A Study in Healthy Subjects to Assess Drug Availability of 4 Different Formulations of Verinurad and Allopurinol
NCT04550234 ·Status: COMPLETED ·Phase: PHASE1
-
Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?
NCT02237339 ·Status: COMPLETED ·Phase: PHASE4
-
Microalbuminuria and Allopurinol in Type 1 Diabetes
NCT02829177 ·Status: COMPLETED ·Phase: PHASE4
-
Screening and Management of Hyperuricemia in Patients with Chronic Medical Diseases in Assiut University Hospital
NCT06586229 ·Status: NOT_YET_RECRUITING
-
Allopurinol in Acute Coronary Syndrome
NCT01457820 ·Status: TERMINATED ·Phase: PHASE4
-
Crossover Clinical Trial, Randomized, Double Blind, Placebo Controlled Trial
NCT04983160 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinol
NCT01265264 ·Status: COMPLETED ·Phase: PHASE2