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Detection of Minimal Change Esophagitis Using Confocal Laser Endomicroscopy

NCT00954070 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 6

Last updated 2012-12-28

No results posted yet for this study

Summary

This is an observational, prospective and pilot study to determine through confocal endomicroscopy diagnostic microscopic features detectable at the gastroesophageal junction of patients with non-erosive gastroesophageal reflux disease.

The hypothesis is that minimal mucosal changes occur in non-erosive gastroesophageal reflux disease. Although these minimal changes are not always visible on white-light endoscopy, it is detectable using high-resolution confocal endomicroscopy and these confocal features are diagnostic of non-erosive reflux disease (NERD).

Conditions

  • Gastroesophageal Reflux Disease

Interventions

DEVICE

Confocal endomicroscope (Pentax Model EC3870K)

The intervention is an endoscopy procedure using a novel type of endoscope with a powerful confocal microscope attached to its tip. The endoscope (Pentax Model EC3870K) provides both white-light and confocal microscopic imaging.

Sponsors & Collaborators

  • National University Hospital, Singapore

    lead OTHER

Principal Investigators

  • Khek Yu Ho, MD · National University Hospital, Singapore

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2012-04-30
Completion
2012-04-30

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00954070 on ClinicalTrials.gov