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Cataract Removal and Alzheimer's Disease

NCT00921297 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 122

Last updated 2017-11-09

No results posted yet for this study

Summary

Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person. Although a cure for AD is currently unavailable, cataracts can be effectively treated with surgery in most people. The removal of cataracts has documented benefits for visual performance and for reducing accidents and falls. However, it has been the experience of the ophthalmologists, and others in the field, that patients, caregivers, and primary care doctors are reluctant to proceed with cataract surgery once an individual is given the diagnosis of AD. It is thought that cataract surgery will not improve the AD patient's quality of life, vision, and cognition. The investigators have designed this study to determine whether or not this is true.

Conditions

Interventions

PROCEDURE

Immediate Cataract Surgery

Cataract surgery, as part of standard of care, will be performed on 1/2 of the group under investigation.

Sponsors & Collaborators

  • Case Western Reserve University

    collaborator OTHER

  • MetroHealth Medical Center

    collaborator OTHER

  • National Institute on Aging (NIA)

    collaborator NIH

  • University Hospitals Cleveland Medical Center

    lead OTHER

Principal Investigators

  • Grover C. Gilmore, PhD. · Case Western Reserve University

  • Sara Debanne, PhD. · Case Western Reserve University

  • Julie Belkin, M.D. · University Hospitals Cleveland Medical Center

  • Jonathan Lass, M.D. · University Hospitals Cleveland Medical Center

  • Alan Lerner, M.D. · University Hospitals Cleveland Medical Center

  • Thomas Steinemann, M.D. · MetroHealth Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-06-30
Primary Completion
2017-03-30
Completion
2017-03-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00921297 on ClinicalTrials.gov