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Spectroscopy of Breast Tissue

NCT00918216 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 141

Last updated 2014-07-16

No results posted yet for this study

Summary

RATIONALE: Diagnostic procedures, such as laser spectroscopy, may help find and diagnose breast cancer.

PURPOSE: This phase I trial is studying laser spectroscopy to see how well it works in diagnosing breast cancer in women with breast lesions.

Conditions

Interventions

GENETIC

fluorescence in situ hybridization

Additional histochemical, immunohistochemical, and fluorescence in situ stains may be performed to support the diagnosis or to better understand the spectroscopy results.

OTHER

immunohistochemistry staining method

Additional histochemical, immunohistochemical, and fluorescence in situ stains may be performed to support the diagnosis or to better understand the spectroscopy results.

OTHER

medical chart review

Patients' medical charts are reviewed to obtain clinical information

PROCEDURE

fluorescence spectroscopy

The freshly excised breast tissue samples are analyzed ex vivo by fluorescence, reflectance, and/or Raman spectroscopy.

PROCEDURE

histopathologic examination

Hematoxylin and eosin stained sections of the tissue samples are examined by light microscopy for histopathological analysis.

PROCEDURE

light-scattering spectroscopy

The freshly excised breast tissue samples are analyzed ex vivo by fluorescence, reflectance, and/or Raman spectroscopy.

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Case Comprehensive Cancer Center

    lead OTHER

Principal Investigators

  • Maryann Fitzmaurice, MD · Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-03-31
Primary Completion
2013-10-31
Completion
2013-10-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00918216 on ClinicalTrials.gov