Glutathione and Its Precursors in HIV-Infected Patients
NCT00910442 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 32
Last updated 2009-05-29
Summary
The aim of this study is to investigate the responses of the serum amyloid A (SAA) pathway to dietary supplements of glutamine (Gln) and cysteine (Cys) together with methionine (Met)-overloading in HIV+ patients comparatively to healthy controls.
Conditions
- HIV Infection
Interventions
- DIETARY_SUPPLEMENT
-
Glutathione precursors
HIV+ patients were assigned to 7 day diets containing either NAC or Gln
Sponsors & Collaborators
-
Fundação de Amparo à Pesquisa do Estado de São Paulo
collaborator OTHER_GOV -
UPECLIN HC FM Botucatu Unesp
lead OTHER
Principal Investigators
-
Roberto C Burini, PhD · UNESP Medical School
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-02-28
- Primary Completion
- 2007-02-28
- Completion
- 2009-02-28
More Related Trials
-
Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents
NCT04005053 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels
NCT01251315 ·Status: COMPLETED ·Phase: PHASE1
-
Glutathione (GSH) Supplementation After Hospitalization
NCT03166371 ·Status: WITHDRAWN ·Phase: NA
-
Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19
NCT04703036 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Dietary Effects of Sulfur Amino Acids
NCT00228618 ·Status: COMPLETED
-
Oral Liposomal Glutathione Supplementation in Healthy Subjects
NCT02278822 ·Status: COMPLETED ·Phase: NA
-
Effects of Glutathione (an Antioxidant) and N-Acetylcysteine on Inflammation
NCT01550432 ·Status: COMPLETED ·Phase: NA
-
Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease
NCT04740580 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
GSH Supplementation on Cold/Flu Symptoms in Older Healthy Adults
NCT02316925 ·Status: WITHDRAWN ·Phase: NA
-
The Role of Glutathione Deficiency and MSIDS Variables in Long COVID-19
NCT05371288 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Dietary Methionine and Cysteine Restriction in Healthy Adults
NCT02192437 ·Status: COMPLETED ·Phase: NA
-
Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels
NCT05241262 ·Status: RECRUITING ·Phase: PHASE1
-
L-cysteine Prevents Stomach Exposure to Carcinogenic Acetaldehyde
NCT02524262 ·Status: COMPLETED ·Phase: PHASE2
-
Glutathione in Mild Cognitive Impairment
NCT03493178 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Glutamine Supplementation and Short-term Mortality in Covid-19
NCT04909905 ·Status: COMPLETED ·Phase: PHASE3
-
Glutathione and Fuel Oxidation in Aging
NCT01870193 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1)
NCT02583672 ·Status: COMPLETED ·Phase: PHASE2
-
The Effects of N-acetylcysteine on Performance and Redox Homeostasis
NCT03121222 ·Status: COMPLETED ·Phase: PHASE2
-
Glutathione and Health With Post-Polio Syndrome
NCT01402570 ·Status: COMPLETED ·Phase: NA
-
A Comparison of the Metabolic Effects of Zinc-Amino Acid (ZnAA) Versus Zinc Gluconate
NCT06348056 ·Status: RECRUITING ·Phase: NA
-
The Efficacy and Safety of an Amino Acid Supplement in Adults
NCT05599282 ·Status: COMPLETED ·Phase: PHASE2
-
Vitamin B-6 and Glutathione on Inflammation, Homocysteine, Oxidative Stress and Antioxidant Capacities
NCT02321579 ·Status: UNKNOWN ·Phase: NA
-
Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
NCT04542161 ·Status: RECRUITING ·Phase: PHASE2
-
Sublingual L-GSH Supplementation in Male Subjects With Smoking Habit and/or Hypertension
NCT02125045 ·Status: COMPLETED ·Phase: PHASE3
-
High-dose Ascorbic Acid Intravenous Injection Decreases Mitochondrial DNA Damage in Chronic Fatigue Patients: Randomized-controlled Study
NCT01926132 ·Status: UNKNOWN ·Phase: PHASE4