MedTrace Logo

Study of Latent Tuberculosis Infection (LTBI) by High Resolution Scanner

NCT00904956 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2011-07-11

No results posted yet for this study

Summary

It is traditionally considered that someone with a positive tuberculin skin test (TST) (and/or positive result in Cell Interferon-Gamma Release Assay (TIGRA), depending on the different countries' guidelines) is infected but not ill when the absence of lesions is demonstrated in a thorax X-Ray assay. Even though, the experiences described in literature using cows and pigs as animal models for the study of LTBI demonstrate the presence of this kind of lesion in the animals, even too small to be detected by X-Ray assay, which would suggest they also could happen in human LTBI. Nowadays, the High Resolution Scanners (HR TC) offer the possibility of detecting any lesion approximately 1 mm in diameter, so the investigators plan to use this technique to screen people already infected by M. tuberculosis (but not ill, following the Diagnosis Standard Guidelines).

Additional pathological analysis of resected and post-mortem tissues will provide lesion-based profiles of humans infected with tuberculosis.

Conditions

Sponsors & Collaborators

  • CIBERES CRP-TB program

    collaborator UNKNOWN

  • Germans Trias i Pujol Hospital

    lead OTHER

Principal Investigators

  • Pere-Joan Cardona, MD, PhD · Fundació Institut Germans Trias i Pujol

  • Cristina Vilaplana, MD, PhD · Fundació Institut Germans Trias i Pujol

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-11-30
Primary Completion
2012-06-30
Completion
2012-12-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00904956 on ClinicalTrials.gov