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Iron Overload in Patients Undergoing Donor Stem Cell Transplant

NCT00888316 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 112

Last updated 2017-12-02

No results posted yet for this study

Summary

RATIONALE: Learning about the effect of excess iron in the liver of patients undergoing donor stem cell transplant may help doctors plan treatment.

PURPOSE: This study is investigating the effects of iron overload in patients undergoing donor stem cell transplant.

Conditions

  • Cancer
  • Hematopoietic Stem Cell Transplantation
  • Allogeneic Hematopoietic Cell Transplantation

Interventions

PROCEDURE

magnetic resonance imaging

MRI of the liver will be performed within 30 days prior to HSCT (day 0) and can be done during receipt of conditioning regimen chemotherapy and/or radiation therapy. MRI will also be performed in selected patients at 1 year post-HSCT. This MRI will be done within ± 30 days of their 1-year post-transplant followup date. The R2 MRI is a specific MRI technique and cannot be used for the purpose of general diagnostic imaging. In our study, this modality is being used specifically for the estimation of LIC.

PROCEDURE

Serum ferritin

Blood samples will be taken pre-transplant, 3, 6, 9 and 12 months post-transplant

Sponsors & Collaborators

  • Masonic Cancer Center, University of Minnesota

    lead OTHER

Principal Investigators

  • Linda Burns, M.D. · Masonic Cancer Center, University of Minnesota

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-12-31
Primary Completion
2012-06-30
Completion
2012-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00888316 on ClinicalTrials.gov