Paclitaxel-Loaded Polymeric Micelle and Carboplatin as First-Line Therapy in Treating Patients With Advanced Ovarian Cancer
NCT00886717 · Status: UNKNOWN · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 74
Last updated 2013-08-02
Summary
RATIONALE: Drugs used in chemotherapy, such as paclitaxel-loaded polymeric micelle and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells.
PURPOSE: This phase I/II trial is studying the side effects and best dose of paclitaxel-loaded polymeric micelle and carboplatin and to see how well they work as first-line therapy in treating patients with advanced ovarian cancer.
Conditions
Interventions
- DRUG
- DRUG
-
paclitaxel-loaded polymeric micelle
Sponsors & Collaborators
-
Asan Medical Center
lead OTHER
Principal Investigators
-
Yong Man Kim, MD, PhD · Asan Medical Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-05-31
Countries
- South Korea
Study Locations
More Related Trials
-
A Phase IIclinical Trial of Carboplatin and Paclitaxel or Carboplatin and Gemcitabine in Platinum-sensitive, Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
NCT01570582 ·Status: UNKNOWN ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer
NCT00005046 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer
NCT00011986 ·Status: COMPLETED ·Phase: PHASE3
-
Paclitaxel in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer
NCT00023907 ·Status: TERMINATED ·Phase: PHASE2
-
Gemcitabine and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer That Responded to Previous Cisplatin or Carboplatin
NCT00369954 ·Status: WITHDRAWN ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Untreated Ovarian, Peritoneal, or Fallopian Tube Cancer
NCT00003385 ·Status: COMPLETED ·Phase: PHASE1
-
Anlotinib Combined With Carboplatin/Paclitaxel as First-line Treatment in Patients With Advanced Ovarian Cancer
NCT04807166 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Intraperitoneal Therapy For Ovarian Cancer With Carboplatin Trial
NCT01506856 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Cancer
NCT00003732 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy With CS-1008 to Treat Ovarian Cancer
NCT00945191 ·Status: COMPLETED ·Phase: PHASE2
-
Taxol/ Carboplatin as First Line Therapy in Patients With Epithelial Ovarian Cancer
NCT00170664 ·Status: COMPLETED ·Phase: PHASE2
-
Polyglutamate Paclitaxel and Carboplatin in Treating Patients With Ovarian Epithelial, Peritoneal, or Fallopian Tube Cancer
NCT00060359 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Paclitaxel (Albumin-bound) Combination With Carboplatin in Ovarian Cancer.
NCT04661696 ·Status: UNKNOWN ·Phase: PHASE2
-
Carboplatin Plus Paclitaxel or Docetaxel in Treating Patients With Ovarian Epithelial Cancer
NCT00003998 ·Status: COMPLETED ·Phase: PHASE3
-
Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
NCT02101775 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma
NCT02437812 ·Status: UNKNOWN ·Phase: PHASE2
-
Paclitaxel and Cisplatin in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal Cancer
NCT00002717 ·Status: COMPLETED ·Phase: PHASE3
-
Lower Dose Decitabine (DAC)-Primed TC (Carboplatin-Paclitaxel) Regimen in Ovary Cancer
NCT02159820 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Paclitaxel Plus Carboplatin With or Without Topotecan in Treating Patients With Stage IIB, Stage III, or Stage IV Ovarian Epithelial Cancer
NCT00006454 ·Status: COMPLETED ·Phase: PHASE3
-
Platinum-based Chemotherapy With or Without Paclitaxel in Treating Patients With Relapsed Ovarian Cancer
NCT00002894 ·Status: COMPLETED ·Phase: PHASE3
-
Nab-paclitaxel Versus Sb-taxanes As First-Line Treatment in Advanced Ovarian Cancer
NCT05737303 ·Status: RECRUITING ·Phase: PHASE3
-
Combination Chemotherapy in Treating Patients With Platinum-Resistant Recurrent Ovarian Cancer
NCT00003449 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin Plus Paclitaxel With or Without Continued Low-Dose Paclitaxel in Treating Patients With Early-Stage Ovarian Cancer
NCT00003644 ·Status: COMPLETED ·Phase: PHASE3
-
Two Different Schedules of Carboplatin, Paclitaxel, Gemcitabine, and Surgery in Treating Patients With Newly Diagnosed Stage IIIC or Stage IV Primary Epithelial Ovarian Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
NCT00838656 ·Status: UNKNOWN ·Phase: PHASE2
-
Paclitaxel and Carboplatin With Or Without Sorafenib In The First-Line Treatment Of Patients With Ovarian Cancer
NCT00390611 ·Status: COMPLETED ·Phase: PHASE2