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Prevention of the Hepatic Sinusoidal Obstruction Syndrome by Means of Anticoagulants

NCT00885950 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2014-02-04

No results posted yet for this study

Summary

The purpose of the study is to determine whether anticoagulant use (i.e. salicylates, clopidogrel, low-molecular weight heparin, or coumarin derivates) is able to prevent the development of the sinusoidal obstruction syndrome secondary to oxaliplatin-based neoadjuvant chemotherapy in patients suffering from colorectal liver metastases.

Conditions

  • Sinusoidal Obstruction Syndrome
  • Colorectal Liver Metastases

Sponsors & Collaborators

  • Maastricht University Medical Center

    lead OTHER

Principal Investigators

  • Steven WM Olde Damink, MD, PhD, MSc · Maastricht University Medical Centre

  • Rob Jansen, MD, PhD · Maastricht University Medical Centre

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2009-12-31
Completion
2010-06-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00885950 on ClinicalTrials.gov