A Multicenter Prospective Study of Quality of Life in Adult Scoliosis

Summary

This is a multicenter study evaluating the effectiveness of nonoperative and operative treatments. The investigators wish to identify important clinical and radiographic determinants of outcomes in the management of adults with symptomatic lumbar scoliosis (ASLS).

Note: Enrollment was complete July 2014. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) funding ended 2/28/17. We continue to follow enrolled subjects while we seek additional funding to follow all subjects through 8 years.

Conditions

• Scoliosis

Interventions

PROCEDURE

Surgical intervention

Surgical intervention as appropriate for adults with symptomatic lumbar scoliosis

OTHER

Non-operative intervention

Non operative intervention as appropriate for treatment of adults with symptomatic lumbar scoliosis such as: injections, medications, physical therapy, etc.

Sponsors & Collaborators

• National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

  collaborator NIH

• Northwestern University

  collaborator OTHER

• New York University

  collaborator OTHER

• University of Virginia

  collaborator OTHER

• University of Louisville

  collaborator OTHER

• Maryland Spine Center

  collaborator OTHER

• Hospital for Special Surgery, New York

  collaborator OTHER

• University Health Network, Toronto

  collaborator OTHER

• Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

  collaborator OTHER

• Dartmouth College

  collaborator OTHER

• Washington University School of Medicine

  lead OTHER

Principal Investigators

• Keith H Bridwell, MD · Washington University School of Medicine

• Jon Lurie, MD · Dartmouth-Hitchcock Medical Center

• Christopher Shaffrey, MD · University of Virginia

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

40 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2010-04-30

Primary Completion

2017-02-28

Completion

2017-02-28

Countries

• United States
• Canada

Study Locations