Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine
NCT00847418 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2010-12-02
Summary
The purpose of this study is the determination of blood concentration and the effectiveness of esketamine after nasal application.
Conditions
Interventions
- DRUG
-
esketamine hydrochloride
Sponsors & Collaborators
-
University Hospital, Basel, Switzerland
lead OTHER
Principal Investigators
-
Manuel Haschke, MD · Clinical Pharmacology and Toxicology, University Hospital Basel
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-02-28
- Completion
- 2009-10-31
Countries
- Switzerland
Study Locations
More Related Trials
-
Low Dose Ketamine Intra Nasal Traumatology
NCT03233035 ·Status: COMPLETED ·Phase: PHASE2
-
Acute Dose-dependent Effects of DMT in Healthy Subjects
NCT05384678 ·Status: COMPLETED ·Phase: PHASE1
-
Acute Analgesic Effects of DMT on Experimentally Induced Pain in Healthy Participants
NCT06180759 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Effects of Esketamine on Cardiac Repolarization in Healthy Participants
NCT02737605 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Different Modes of (S) Ketamine Administration in Healthy Participants
NCT03808259 ·Status: COMPLETED ·Phase: PHASE1
-
Emotional Effects of Methylphenidate and MDMA in Healthy Subjects
NCT01465685 ·Status: COMPLETED ·Phase: PHASE1
-
Temporal Dynamics and Pharmacokinetics of Intranasally Administered Oxytocin
NCT03011970 ·Status: COMPLETED ·Phase: PHASE1
-
Influence of Bupropion on the Effects of MDMA
NCT01771874 ·Status: COMPLETED ·Phase: PHASE1
-
A Mass Balance Study With a Microtracer Dose of 14C-esketamine in Healthy Male Participants
NCT02674295 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants
NCT02228239 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers
NCT05698095 ·Status: COMPLETED ·Phase: PHASE1
-
Acute Effects of 3,4-methylenedioxymethamphetamine (MDMA) With and Without a Booster Dose
NCT05809271 ·Status: COMPLETED ·Phase: PHASE1
-
Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD
NCT07309471 ·Status: RECRUITING ·Phase: NA
-
Methamphetamine Isomer Pharmacology in Humans
NCT06746831 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)
NCT00990067 ·Status: COMPLETED ·Phase: PHASE1
-
Explorative Efficacy Profile of Neurexan® in an Experimental Acute Stress Setting in Healthy Subjects
NCT01703819 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effects of MDMA-like Substances in Healthy Subjects
NCT04847206 ·Status: COMPLETED ·Phase: PHASE1
-
Dose-finding Study for the Combination of DMT and Harmine in Healthy Subjects
NCT05829603 ·Status: COMPLETED ·Phase: PHASE1
-
Safety of GH001 in Healthy Volunteers
NCT04640831 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
NCT01951508 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Endogenous Opioid Modulation by Ketamine
NCT03051945 ·Status: WITHDRAWN ·Phase: PHASE3
-
The Effects of Fentanyl Abuse on Executive Function and Related Brain Activity
NCT05469217 ·Status: UNKNOWN
-
Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)
NCT01136278 ·Status: COMPLETED ·Phase: PHASE1
-
Changes in Striatal [11C]ORM-13070 Binding Elicited by Changing Levels of Endogenous Noradrenaline
NCT01794975 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of H1-Antagonist on Cognition
NCT00846950 ·Status: COMPLETED ·Phase: NA