Vocal Acoustic Biomarkers in Depression
NCT00844948 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 125
Last updated 2012-05-07
Summary
This Phase II SBIR study will replicate pilot study methods establishing computer-automated methods for assessing depression severity using interactive voice response system technology and demonstrating feasibility of obtaining measures of depression severity and treatment response through vocal acoustic analysis of speech samples obtained over the telephone. The study will automate vocal acoustic analysis methods, evaluate applicability to other patient populations (non-English speakers, children/young adult, and geriatric), and further develop multivariate acoustic models to enhance biomarker sensitivity to treatment response and prediction of the response likelihood for individual patients.
Conditions
Sponsors & Collaborators
-
Massachusetts General Hospital
collaborator OTHER -
National Institute of Mental Health (NIMH)
collaborator NIH -
Center for Psychological Research, Madison, WI
lead OTHER
Principal Investigators
-
James C Mundt, PhD · Center for Psychological Research, Training and Consultation
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-10-31
- Primary Completion
- 2011-06-30
- Completion
- 2012-04-30
Countries
- United States
Study Locations
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