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Effects of Coffee on Hepatic Steatosis Induced by a High Fructose Diet

NCT00827450 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2012-02-24

No results posted yet for this study

Summary

This study will assess

* whether coffee consumption protects against fructose-induced hepatic steatosis in healthy humans
* whether the protective effect of coffee is dependent on it's antioxidant composition

Conditions

  • Hepatic Steatosis

Interventions

DIETARY_SUPPLEMENT

Ctl

Control, isocaloric diet; no coffee

DIETARY_SUPPLEMENT

High fructose diet; no coffee

Hypercaloric, high fructose diet; no coffee

DIETARY_SUPPLEMENT

fully torrefied, caffeine-free coffee

Hypercaloric, high fructose diet + coffee

DIETARY_SUPPLEMENT

partially torrefied, caffeine-free coffee

Hypercaloric, high fructose diet + coffee

DIETARY_SUPPLEMENT

Partially torrefied, caffeinated coffee

Hypercaloric, high fructose diet + coffee

Sponsors & Collaborators

  • Nestlé Research Center, Vers-chez-les-blanc, Switzerland

    collaborator UNKNOWN

  • University of Lausanne

    lead OTHER

Principal Investigators

  • Luc Tappy, MD · Department of Physiology, University of Lausanne, Switzerland

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-02-28
Primary Completion
2010-12-31
Completion
2011-03-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00827450 on ClinicalTrials.gov