Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2)
NCT00824057 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2009-07-31
Summary
The aim of this study is to investigate the effects of taking repeated doses of AZD6280 on the blood levels of midazolam and caffeine in healthy volunteers
Conditions
- Healthy
Interventions
- DRUG
-
AZD6280
oral
- DRUG
-
Midazolam
oral
- DRUG
-
Caffeine
oral
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Darren Wilbraham, MBBS, DCPSA · Guy's Drug Research Unit Quintiles Ltd
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- QUADRUPLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-01-31
- Completion
- 2009-03-31
Countries
- United Kingdom
Study Locations
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