Study of Statin as Neo-Adjuvant Therapy in Postmenopausal Breast Cancer
NCT00816244 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2012-04-13
Summary
The purpose of this study is to monitor:
* Tumor biological alterations following two weeks of neo-adjuvant statin therapy.
* Effects of statins on tumor proliferation.
* Functional studies on the mevalonate pathway.
Conditions
- Breast Cancer
- Postmenopausal
Interventions
- DRUG
-
Atorvastatin 80 mg daily for two weeks, ending at the day of operation for breast cancer.
Sponsors & Collaborators
-
Lund University Hospital
lead OTHER
Principal Investigators
-
Carsten Rose, MD · University Hospital Lund
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-01-31
- Primary Completion
- 2012-03-31
- Completion
- 2012-03-31
Countries
- Sweden
Study Locations
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