Study of the Relationship Between Sleep Quality and Daytime-Nighttime Variations of Blood Pressure and Plasma Glucose Type I

Summary

The primary objectives are to compare the mean levels of the sleep quality parameters of subjects : with a nocturnal fall of the SBP (Systolic blood pressure), DBP (diastolic blood pressure) and MAP (mean arterial pressure) over of egal to 10% (dipping subjects) and of subjects with a nocturnal fall of SBP, DBP and MAP inferior to 10% (non dipper subjects).

The secondary objectives are :

Establish correlations between:

* The quality of sleep parameters
* The parameters of BP variations between the diurnal and nocturnal periods and the awake periods of sleep defined in reference to polysomnography.
* The glycemia levels on 24h with a glycemic holter. The parameters of the sympathic system activation evaluated in reference to the measure of the baroreflex sensibility during the awake period.

Conditions

• Type 1 Diabetes

Interventions

BIOLOGICAL

Biological examinations (blood and urinary).

Sponsors & Collaborators

• Pr Mallion Jean-Michel

  collaborator UNKNOWN

• Pr BAGUET Jean-Philippe

  collaborator UNKNOWN

• Pr BENHAMOU Pierre-Yves

  collaborator UNKNOWN

• Pr LEVY Patrick

  collaborator UNKNOWN

• Dr MOURET Sandrine

  collaborator UNKNOWN

• Dr ORMEZZANO Olivier

  collaborator UNKNOWN

• Pr PEPIN Jean-Louis

  collaborator UNKNOWN

• Dr TAMISIER Renaud

  collaborator UNKNOWN

• University Hospital, Grenoble

  lead OTHER

Principal Investigators

• MALLION Jean-Michel, Pr · University Hospital, Grenoble

Study Design

Allocation

NA

Purpose

SCREENING

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2005-10-31

Primary Completion

2007-12-31

Completion

2007-12-31

Countries

• France

Study Locations