Docetaxel and Hydroxychloroquine in Treating Patients With Metastatic Prostate Cancer
NCT00786682 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 11
Last updated 2023-08-14
Summary
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Hydroxychloroquine may help docetaxel work better and kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving docetaxel together with hydroxychloroquine works in treating patients with metastatic prostate cancer.
Conditions
Interventions
- DRUG
- DRUG
-
hydroxychloroquine
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Medicine and Dentistry of New Jersey
lead OTHER
Principal Investigators
-
Mark Stein, MD · Rutgers Cancer Institute of New Jersey
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 120 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-12-31
- Primary Completion
- 2012-10-31
- Completion
- 2012-10-31
Countries
- United States
Study Locations
More Related Trials
-
Docetaxel, Prednisone, and Pasireotide in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
NCT01468532 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Docetaxel and Prednisone in Treating Patients With Hormone-Refractory Metastatic Prostate Cancer
NCT00255606 ·Status: COMPLETED ·Phase: PHASE3
-
Docetaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer
NCT00002775 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Navitoclax and Abiraterone Acetate With or Without Hydroxychloroquine in Treating Patients With Progressive Metastatic Castrate Refractory Prostate Cancer
NCT01828476 ·Status: TERMINATED ·Phase: PHASE2
-
Docetaxel in Treating Patients With Relapsed Prostate Cancer
NCT00482274 ·Status: TERMINATED ·Phase: PHASE2
-
Docetaxel, Doxorubicin, and Prednisone in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00416533 ·Status: COMPLETED ·Phase: PHASE2
-
Methylprednisolone With or Without Doxorubicin in Treating Patients With Metastatic Prostate Cancer
NCT00003682 ·Status: TERMINATED ·Phase: PHASE3
-
Docetaxel in Treating Patients With Stage IV Prostate Cancer
NCT00003781 ·Status: COMPLETED ·Phase: PHASE2
-
DHA-Paclitaxel in Treating Patients With Metastatic Prostate Cancer
NCT00024414 ·Status: UNKNOWN ·Phase: PHASE2
-
Combination of Docetaxel + Estramustine + Hydrocortisone Versus Docetaxel + Prednisone in Patients With Advanced Prostate Cancer
NCT00705822 ·Status: TERMINATED ·Phase: PHASE3
-
Hsp90 Inhibitor STA-9090 in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy
NCT01270880 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Dasatinib and Docetaxel in Metastatic Hormone Refractory Prostate Cancer
NCT00439270 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate Cancer
NCT00027859 ·Status: COMPLETED ·Phase: PHASE3
-
Docetaxel and Cetuximab in Treating Patients With Metastatic Prostate Cancer
NCT00728663 ·Status: COMPLETED ·Phase: PHASE2
-
Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer
NCT00587431 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer
NCT03513211 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Androgen Deprivation Therapy Combined With Docetaxel for High Risk Prostate Cancer
NCT04869371 ·Status: UNKNOWN ·Phase: PHASE2
-
Docetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00052845 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy With or Without Biological Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00005847 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy in Treating Patients With Prostate Cancer
NCT00004045 ·Status: COMPLETED ·Phase: PHASE2
-
Phenelzine Sulfate and Docetaxel in Treating Patients With Prostate Cancer With Progressive Disease After First-Line Therapy With Docetaxel
NCT01253642 ·Status: TERMINATED ·Phase: PHASE2
-
PII Trial of Docetaxel/Prednisone w/Sargramostim for HRPC
NCT00313482 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of Docetaxel Plus Carboplatin in Patients With Hormone Refractory Prostate Cancer
NCT00134706 ·Status: COMPLETED ·Phase: PHASE2
-
Intravenous CG7870 in Combination With Docetaxel in Patients With Metastatic Hormone-Refractory Prostate Cancer
NCT00103428 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
NCT00005960 ·Status: UNKNOWN ·Phase: PHASE2