In Vivo Confocal Microscopy for Pigmented Lesion Diagnosis

Summary

The purpose of this study is to image pigmented skin lesions suspicious for melanoma with an imaging technology called in vivo reflectance confocal microscopy. This technology uses low intensity laser to image below the surface of the skin. The confocal images of the suspicious skin lesion will be examined. The goal of this study is to compare the results of the confocal image examination to the pathologic diagnosis of the skin lesion.

The technique being evaluated in this study uses reflectance confocal microscopy in vivo. The term "in vivo" means in/on a living subject. In this study you will be the living subject and the confocal microscope will be placed on your skin to look at your skin lesion. The confocal microscope uses a weak laser light and a sophisticated lens to image the individual cells that make up the skin. Your lesion will be photographed with high resolution photography.

Conditions

• Skin Cancer
• Melanoma
• Lentigo Maligna

Interventions

DEVICE

Reflectance confocal microscopy

Reflectance confocal microscopy (VivaScope 1500)

Sponsors & Collaborators

• Memorial Sloan Kettering Cancer Center

  collaborator OTHER

• Loma Linda University

  collaborator OTHER

• University of Rochester

  collaborator OTHER

• VA Loma Linda Health Care System

  collaborator FED

• Skin and Cancer Associates in Plantation,Fl.

  collaborator UNKNOWN

• Harvard University

  collaborator OTHER

• Lucid, Inc.

  lead INDUSTRY

Principal Investigators

• Allan C Halpern, MD · Memorial Sloan-Kettering Cancer Center, Manhattan

• Ashfaq Marghoob, MD · Memorial Sloan Kettering Cancer Center, Hauppauge

• Abel Torres, MD · Loma Linda Univeristy Adventist Health Sciences Center

• Lisa Beck, MD · University of Rochester

• Harold S Rabinovitz, MD · Skin and Cancer Associates, Plantation Fl.

• Abel Torres, MD · VA Loma Linda Health Care System

Study Design

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2008-08-31

Primary Completion

2009-12-31

Completion

2009-12-31

Countries

• United States

Study Locations