MedTrace Logo

Vitamin K Supplement for Inhibition of the Progress in Aortic Valve Calcification

NCT00785109 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 99

Last updated 2017-04-21

No results posted yet for this study

Summary

In this mono-center,open,three-armes, controlled, randomized phase I study the progress of aortic valve calcification with and without vitamin K supplementation will be investgated. This will be done by means of measurements of concentrations from osteocalcine and MPG in blood serum, echocardiography, cardiac computed tomography and cardiac MRI

Conditions

  • Aortic Valve Calcification

Interventions

DIETARY_SUPPLEMENT

Vitamin K supplementation

Daily vitamin K supplementation per os (2 mg once a day)Experimental 1 Placebo Experimental 2

Sponsors & Collaborators

  • RWTH Aachen University

    lead OTHER

Principal Investigators

  • Ralf Koos, MD · RWTH Aachen University Departement of Cardiology, Pulmonology and Vascular Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-01-31
Primary Completion
2015-08-31
Completion
2015-08-31

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00785109 on ClinicalTrials.gov