Trial Outcomes & Findings for Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation (NCT NCT00780481)
NCT ID: NCT00780481
Last Updated: 2017-07-14
Results Overview
tPA Release
TERMINATED
NA
13 participants
Single Study day
2017-07-14
Participant Flow
The data for this study was lost. The total number of participants enrolled/completed was pulled from IRB records. Participant age was between 18-65 per protocol. All participants were enrolled in the United States. No other data is available
Participant milestones
| Measure |
Bradykinin
Patients will have flow mediated vasodilation and radial artery tonometry performed. They will then receive 0, 10, 20, 40 ng/100cc/min of intrabrachial bradykinin. Strain gauge plethysmography and blood sampling at each dose will be done to evaluate t-PA release. Blood will also be drawn for other biomarkers.
Bradykinin: Intrabrachial - 0, 10, 20, 40 ng/100cc/min over 5 minutes at each dose.
|
|---|---|
|
Overall Study
STARTED
|
13
|
|
Overall Study
COMPLETED
|
13
|
|
Overall Study
NOT COMPLETED
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Characterization of Brachial Arterial t-PA Release, Endothelial Function, Obesity and Inflammation
Baseline characteristics by cohort
| Measure |
Bradykinin
n=13 Participants
Patients will have flow mediated vasodilation and radial artery tonometry performed. They will then receive 0, 10, 20, 40 ng/100cc/min of intrabrachial bradykinin. Strain gauge plethysmography and blood sampling at each dose will be done to evaluate t-PA release. Blood will also be drawn for other biomarkers.
Bradykinin: Intrabrachial - 0, 10, 20, 40 ng/100cc/min over 5 minutes at each dose.
|
|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=13 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
13 Participants
n=13 Participants
|
|
Age, Categorical
>=65 years
|
0 Participants
n=13 Participants
|
|
Region of Enrollment
United States
|
13 participants
n=13 Participants
|
PRIMARY outcome
Timeframe: Single Study dayPopulation: Data was lost
tPA Release
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Single Study DayPopulation: Data Lost
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Single Study VisitPopulation: Data was lost
Outcome measures
Outcome data not reported
SECONDARY outcome
Timeframe: Single Study DayPopulation: Data was lost
Outcome measures
Outcome data not reported
Adverse Events
Bradykinin
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place