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Melatonin Production Delay in Preterm Infants

NCT00775723 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 46

Last updated 2008-11-03

No results posted yet for this study

Summary

Objective: Melatonin production is known to be delayed in preterm-born infants up to 6 months of age. This might be related to exposure of preterm infants to continuous lighting in the NICU during a critical period of pineal gland development. The investigators aimed to test the profile of melatonin production in these infants at 9-12 months of age.

Methods: Twenty three term-born and 23 preterm-born infants (gestational age: 29-34 weeks) were studied. The investigators tested nocturnal urinary melatonin excretion, within a repeated measures design, both at 9 and 12 months of age. Nocturnal urine was extracted from diapers and urinary melatonin derivate (6-sulphatoxymelatonin) excretion was analyzed by ELISA assay.

Conditions

  • Melatonin Production

Sponsors & Collaborators

  • Tel Aviv University

    lead OTHER

Principal Investigators

  • Dr Sari Goldstein Ferber · Sackler School of Medicine, Tel Aviv Universitry

Eligibility

Min Age
9 Months
Max Age
12 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00775723 on ClinicalTrials.gov