Magnetic Resonance Imaging (MRI) Follow-up of Macrophagic Infiltration in MS Patients Treated With Tysabri
NCT00752778 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 8
Last updated 2012-11-12
Summary
To evaluate the diagnosis value of MRI and positon emission tomography (PET) scan for studying macrophagic infiltration and other brain modification in multiple sclerosis (MS) patients treated with Natalizumab (Tysabri).
Conditions
Interventions
- OTHER
-
pet-scan FDG-F18
Sponsors & Collaborators
- collaborator INDUSTRY
-
University Hospital, Strasbourg, France
lead OTHER
Principal Investigators
-
Jérôme DE SEZE, MD · Hôpitaux Universitaires de Strasbourg
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-12-31
- Primary Completion
- 2011-03-31
- Completion
- 2011-03-31
Countries
- France
Study Locations
More Related Trials
-
Multimodal Imaging Signatures of the Biological Mechanisms Underlying Neurodegeneration in Multiple Sclerosis
NCT05633875 ·Status: RECRUITING
-
A Longitudinal Study of Brain Atrophy in MS Patients Over 5 Years
NCT01847287 ·Status: COMPLETED
-
Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
NCT00001248 ·Status: RECRUITING
-
Clinical Disease Activity With Long Term Natalizumab Treatment
NCT02677077 ·Status: COMPLETED
-
Evaluation of the Positron Emission Tomography (PET) Tracer ZK 6032924 in Patients With Multiple Sclerosis Compared to Healthy Volunteers
NCT01031199 ·Status: COMPLETED ·Phase: PHASE1
-
PET Study in Multiple Sclerosis
NCT03787446 ·Status: UNKNOWN
-
MRI Biomarkers Predictive of Disability Progression in Patients With Multiple Sclerosis
NCT05491031 ·Status: RECRUITING ·Phase: NA
-
Study of Neuroinflammation in Multiple Sclerosis by PET-MRI Imaging Using the Radiotracer ([18F]-DPA-714) : a Multicentre Cohort Study (INFLANET)
NCT06280742 ·Status: RECRUITING ·Phase: NA
-
Examining Effects of Tysabri on Cognitive Fatigue Using fMRI
NCT04565431 ·Status: RECRUITING
-
A Study to Assess the Effects of MK0812 on Disease Activity in Patients With Relapsing-Remitting Multiple Sclerosis as Measured by Magnetic Resonance Imaging (MRI)(0812-003)(COMPLETED)
NCT00239655 ·Status: TERMINATED ·Phase: PHASE2
-
Natalizumab (BG00002, Tysabri) Study in Japanese Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)
NCT01440101 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Evaluation of the Reproducibility of the Measurement of the QSM Signal (Quantitative Susceptibility Mapping)
NCT04465448 ·Status: TERMINATED
-
Diagnostic Study of Quantitative Imaging and Spectroscopy in Patients With Multiple Sclerosis
NCT00006060 ·Status: UNKNOWN
-
Evaluation of an Altered Peptide Ligand (NBI-5788) in Patients With Relapsing Multiple Sclerosis (MS)
NCT00079495 ·Status: COMPLETED ·Phase: PHASE2
-
Extension Study to Evaluate Safety and Efficacy of Natalizumab in Japanese Participants With Relapsing-Remitting Multiple Sclerosis
NCT01416155 ·Status: COMPLETED ·Phase: PHASE2
-
Multimodal Exploration of Patients With Multiple Sclerosis for an Early Detection of Subtle Progression
NCT05941975 ·Status: RECRUITING ·Phase: NA
-
Understanding Magnetic Resonance Imaging in Multiple Sclerosis
NCT03872583 ·Status: COMPLETED ·Phase: NA
-
Natalizumab and Chronic Inflammation
NCT05177718 ·Status: TERMINATED ·Phase: PHASE4
-
Demyelination and Remyelination in Multiple Sclerosis (MS) Detected by Brain Amyloid PET-CT
NCT05783934 ·Status: COMPLETED ·Phase: NA
-
Smoldering Inflammation in MS
NCT06591429 ·Status: RECRUITING
-
Role of Microglial Activation and Norepinephrine Transporter Abnormalities in Pathogenesis of MS-related Fatigue
NCT04144257 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Comparing the Safety and Benefit of Natalizumab (Tysabri®) At-home Infusion vs At-hospital Infusion in Multiple Sclerosis
NCT04777539 ·Status: COMPLETED
-
Remyelination in Multiple Sclerosis: a PET-MR Longitudinal Study Investigating Individual Profiles of Myelin Repair and the Contribution of Neuroinflammation
NCT05147532 ·Status: UNKNOWN ·Phase: NA
-
Multimodal MRI in Multiple Sclerosis (MS): Reliability and Follow Up
NCT00289159 ·Status: UNKNOWN
-
An Efficacy and Safety Study of BG00012 (Dimethyl Fumarate) in Asian Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)
NCT01838668 ·Status: COMPLETED ·Phase: PHASE3