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Low Molecular Weight Heparin in Recurrent Implantation Failure

NCT00750451 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2009-03-20

No results posted yet for this study

Summary

Recurrent implantation failure is the failure to achieve a pregnancy after multiple attempts with in vitro fertilization treatment. The reason is usually obscure. Many empirical treatments have been offered without substantial evaluation. Heparin is thought to play a role in the embryo implantation process beyond its anticoagulation effects. The proposed study aims to assess the effectiveness and safety of empirical administration of low molecular weight heparin in patients undergoing a new IVF treatment cycle after multiple failed attempts.

Conditions

  • Infertility
  • Fertilization in Vitro
  • Recurrent Implantation Failure

Interventions

DRUG

low molecular weight heparin (enoxaparine sodium)

1 mg/kg/day subcutaneously in the luteal phase after IVF treatment

DRUG

crinone 8% gel

routine luteal phase support with progesterone gel

Sponsors & Collaborators

  • V.K.V. American Hospital, Istanbul

    lead OTHER

Principal Investigators

  • Cumhur B Urman, M.D. · American Hospital of Istanbul

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
38 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00750451 on ClinicalTrials.gov