MedTrace Logo

Measurement of MRP2 Function Using Urinary Coproporphyrins

NCT00746044 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2009-05-15

No results posted yet for this study

Summary

Human Multidrug Related Protein 2 (MRP2) excretes several drugs and could therefore modulate their elimination. Individual's MRP2 activity is under genetic control. Thus it would be very useful to get an easily measurable biomarker reflecting individual's MRP2 activity. We aimed to investigate the ratio of urinary coproporphyrins I and III (UCP(I/I+III), known to be increased in patients with mutations in MRP2/ABCC2 gene.

Conditions

  • Healthy Subjects

Sponsors & Collaborators

  • University Hospital, Tours

    lead OTHER

Principal Investigators

  • Chantal LE GUELLEC · CHRU TOURS

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-02-29
Primary Completion
2008-04-30
Completion
2009-04-30

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00746044 on ClinicalTrials.gov