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Assessment of Cardiac Involvement of Common Cold in High Performing Athletes by Cardiac Magnetic Resonance Imaging (MRI)

NCT00739895 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2011-10-04

No results posted yet for this study

Summary

Cardiovascular magnetic resonance (CMR) imaging will be used to assess the impact of common colds and physical training in high-performing athletes. Healthy individuals from the general public will serve as a comparison group. CMR has previously been shown to accurately assess cardiac function, edema, inflammation, and injury.

Athletes competing at National level and Developmental Canadian teams will be prospectively recruited. All participants will have CMR scans at low and high intensity training. Participants will be re-scanned immediately after clinical evidence of a common cold, as determined by respiratory and flu-like symptoms. After 4 weeks, a follow-up CMR scan will be performed. On the day of each CMR scan, electrocardiograms and blood samples will be drawn from each participant. Blood samples will provide markers of systemic inflammation, such as leukocyte counts. At each CMR scan, athletes will be asked to describe there recent history of physical exertion in questionnaires, which will reflect the degree of physical exertion performed.

Conditions

  • Ventricular Function, Left

Interventions

PROCEDURE

Cardiac magnetic Resonance study

follow-up studies

PROCEDURE

Blood testing

Blood sample tested for myocardial biomarkers

Sponsors & Collaborators

  • University of Calgary

    lead OTHER

Principal Investigators

  • Matthias G Friedrich, MD, FESC · University of Calgary

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-06-30
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00739895 on ClinicalTrials.gov