Single Dose Escalation Study of PF-04360365 In Subjects With Mild To Moderate Alzheimer's Disease
NCT00733642 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 15
Last updated 2009-07-28
Summary
The purpose of this study is to determine whether single doses of PF-04360365 is safe and well tolerated in patients with Alzheimer's Disease.
Conditions
Interventions
- BIOLOGICAL
-
PF-04360365 1 mg/kg
PF-04360365 1 mg/kg infused as a single dose
- BIOLOGICAL
-
PF-04360365 3 mg/kg
PF-04360365 3 mg/kg infused as a single dose
- BIOLOGICAL
-
PF-04360365 5 mg/kg
PF-04360365 5 mg/kg infused as a single dose
- BIOLOGICAL
-
PF-04360365 10 mg/kg
PF-04360365 10 mg/kg infused as a single dose
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-08-31
- Primary Completion
- 2009-07-31
- Completion
- 2009-07-31
Countries
- United States
Study Locations
More Related Trials
-
Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.
NCT02793232 ·Status: COMPLETED ·Phase: PHASE1
-
Multiple Intravenous Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease
NCT01125631 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers
NCT01005862 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety and Tolerability Evaluation of Two 10-Week Dose Regimens of Orally-Administered PF-04494700 in Alzheimer's Patients
NCT00141661 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Study for Safety and Tolerability of AL002.
NCT03635047 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of MT-4666
NCT01764243 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single, Oral Escalating Doses of GSK2647544 in Healthy Volunteers
NCT01702467 ·Status: COMPLETED ·Phase: PHASE1
-
Single Ascending Dose Study of BIIB037 in Participants With Alzheimer's Disease
NCT01397539 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease
NCT00766363 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease
NCT00566397 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating The Safety Of AAB-003 (PF-05236812) In Subjects With Alzheimer's Disease
NCT01193608 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)
NCT06402838 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Single Dose Escalation Study of CM383 in Healthy Volunteers
NCT06412185 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Assess the Safety of GRF6019 Infusions in Subjects With Severe Alzheimer's Disease
NCT03765762 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
NCT02423200 ·Status: COMPLETED ·Phase: PHASE2
-
Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)
NCT03740178 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study to Evaluate Safety and Tolerability of Different Doses and Efficacy of PQ912 in Subjects With MCI and Mild AD
NCT04498650 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized, Double-blind, Placebo-controlled, Sequential Ascending, Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2212 in Healthy Subjects
NCT01221259 ·Status: COMPLETED ·Phase: PHASE1
-
Safety Study of PPI-1019 in Patients With Mild-Moderate Alzheimer's Disease
NCT00100282 ·Status: COMPLETED ·Phase: PHASE1
-
Phase1a, Dose-escalation Study of NNI-362 in Healthy Aged Volunteers
NCT04074837 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, and Blood Levels of PF-03654746 in Subjects With Mild to Moderate Alzheimer's Disease
NCT01028911 ·Status: TERMINATED ·Phase: PHASE1
-
Safety and Efficacy Study of AC-3933 in Adults With Mild to Moderate Alzheimer's Disease
NCT00359944 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of PPI-1019 in Subjects With Mild-Moderate Alzheimer's Disease
NCT00100334 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease
NCT01969136 ·Status: TERMINATED ·Phase: PHASE3
-
Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease
NCT01969123 ·Status: TERMINATED ·Phase: PHASE3