Study of PRX-03140 Monotherapy in Subjects With Alzheimer's Disease
NCT00693004 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 236
Last updated 2009-07-30
Summary
A randomized placebo-controlled study to evaluate the efficacy of PRX-03140 monotherapy in subjects with Alzheimer's disease. The study consists of a 3-month double-blind treatment period and an optional 3-month extension period.
Conditions
Interventions
- DRUG
-
PRX-03140
- DRUG
-
Donepezil
- DRUG
Sponsors & Collaborators
-
Epix Pharmaceuticals, Inc.
lead INDUSTRY
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 50 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-05-31
- Primary Completion
- 2010-01-31
Countries
- United States
Study Locations
More Related Trials
-
A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease
NCT00930059 ·Status: COMPLETED ·Phase: PHASE2
-
Safety Study of R(+)Pramipexole to Treat Early Alzheimer's Disease
NCT01388478 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment
NCT03446001 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease
NCT00607308 ·Status: COMPLETED ·Phase: PHASE1
-
Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo
NCT02240693 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Study Evaluating the Efficacy and Safety of RPh201 Treatment in Individuals With Alzheimer's Disease With or Without Coexisting Cerebrovascular Disease
NCT03462121 ·Status: COMPLETED ·Phase: PHASE2
-
Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease
NCT00722046 ·Status: COMPLETED ·Phase: PHASE2
-
Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease
NCT00766363 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)
NCT06402838 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.
NCT02337907 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 3, 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of 2 Fixed Doses of Brexpiprazole in the Treatment of Alzheimer's Agitation
NCT01862640 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Safety and Tolerability of Different Doses and Efficacy of PQ912 in Subjects With MCI and Mild AD
NCT04498650 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Assess Safety and Efficacy of PRI-002 in Patients With MCI to Mild Dementia Due to Alzheimer's Disease (AD)
NCT06182085 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Dose-Finding Study To Evaluate Safety, Tolerability, and Efficacy of E2609 in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (Prodromal Alzheimer's Disease) and Mild to Moderate Dementia Due to Alzheimer's Disease
NCT02322021 ·Status: TERMINATED ·Phase: PHASE2
-
Single Dose Escalation Study of PF-04360365 In Subjects With Mild To Moderate Alzheimer's Disease
NCT00733642 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Evaluating the Efficacy and Safety of Crenezumab Versus Placebo in Participants With Prodromal to Mild Alzheimer's Disease (AD).
NCT02670083 ·Status: TERMINATED ·Phase: PHASE3
-
Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease
NCT03533257 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of Semorinemab in Patients With Prodromal to Mild Alzheimer's Disease
NCT03289143 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease
NCT03131453 ·Status: TERMINATED ·Phase: PHASE2/PHASE3
-
PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD)
NCT06750432 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
NCT02423200 ·Status: COMPLETED ·Phase: PHASE2
-
Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)
NCT01181310 ·Status: COMPLETED ·Phase: PHASE1
-
A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type
NCT03548584 ·Status: COMPLETED ·Phase: PHASE3
-
Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease
NCT05267535 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
A Phase 3 Study of Rotigotine in Combination with Rivastigmine in Mild to Moderate Alzheimer's Disease
NCT06702124 ·Status: RECRUITING ·Phase: PHASE3