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Impact of HIV Infection on Latent Tuberculosis (TB) Among Patients With HIV-TB Co-infection

NCT00692809 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2009-09-15

No results posted yet for this study

Summary

HIV induced altered representation and function of regulatory T cell subsets (NKT and Treg cells) impair the protective T cell response against M.tuberculosis and disrupts LTBI, thus facilitates faster progression and development of severe forms of clinical TB in HIV-TB co-infection.

Conditions

Sponsors & Collaborators

  • Indian Council of Medical Research

    collaborator OTHER_GOV

  • Ministry of Science and Technology, India

    lead OTHER_GOV

Principal Investigators

  • Surendra K Sharma, M.D., Ph.D · All India Institute of Medical Sciences

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-07-31
Primary Completion
2010-03-31
Completion
2010-03-31

Countries

  • India

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00692809 on ClinicalTrials.gov