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Effects of Crestor on Inflammation of Atherosclerotic Plaques

NCT00689416 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 74

Last updated 2009-06-30

No results posted yet for this study

Summary

The primary aim of this study is to investigate the effect of 40 mg dose of rosuvastatin on carotid plaque inflammation measured with MRI and PET scanning, to evaluate whether these techniques are promising for future proof of principle studies. A number of patients will receive placebo as a control.

Conditions

Interventions

DRUG

rosuvastatin

40 mg, tablet, once daily for 3 months.

DRUG

placebo

40 mg, tablet, once daily for 3 months

Sponsors & Collaborators

Principal Investigators

  • Håkan Ahlström, MD, Professor · Uppsala University Sweden

  • Maria Leonsson-Zachrissson, MD, Study Physician · AstraZeneca R&D Mölndal

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-12-31
Completion
2009-06-30

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00689416 on ClinicalTrials.gov