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Evaluation of Formin Gene Status and Expression in Myeloproliferative and Myelodysplastic Disorders

NCT00687414 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2023-07-27

No results posted yet for this study

Summary

Aim of the study is to analyze the expression of genes and sequences encoding the human mammalian diaphanous (mDia) related formin proteins to test the hypothesis that defects in the mDia expression or function might drive the pathophysiology of myelodysplastic syndrome, acute myeloid leukemia and other myeloproliferative diseases.

Conditions

  • Myeloproliferative Disorder
  • MDS
  • AML

Sponsors & Collaborators

  • Van Andel Research Institute

    collaborator OTHER

  • Community Foundation for Southeast Michigan (JP McCarthy Fund)

    collaborator UNKNOWN

  • Spectrum Health Hospitals

    lead OTHER

Principal Investigators

  • Arthur S Alberts, PhD · Van Andel Research Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2008-04-30
Primary Completion
2009-12-31
Completion
2010-01-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00687414 on ClinicalTrials.gov