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Effects of Stress and Other Factors on Opiate Drug Choice.

NCT00684840 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 16

Last updated 2012-06-05

No results posted yet for this study

Summary

The purpose is to study the extent to which stress and other factors, including money, the amount of drug available and the amount of work effort, affect drug choice.

This study will assess whether exposure to yohimbine, a drug stressor, increases opioid craving- and -seeking behavior. We will determine whether these behavioral outcomes are associated with biobehavioral stress markers: increased saliva cortisol levels, cardiovascular response (heart rate and blood pressure), and negative mood state.

Conditions

  • Heroin Dependence
  • Opioid-Related Disorders

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Wayne State University

    lead OTHER

Principal Investigators

  • Mark Greenwald, PhD · Wayne State University

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-03-31
Primary Completion
2011-12-31
Completion
2011-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00684840 on ClinicalTrials.gov